The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. Will those NFL betting trends continue, or is this a week that NFL favorites will thrive? All of the Week 4 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 4 NFL picks now. They're also covering at a 54.5% clip entering this week. They entered the week 19-29 straight-up, returning more than five units of profit. Betting on NFL underdogs has been the profitable route thus far in 2023. The Cowboys (-6), 49ers (-14) and Chiefs (-8) are all listed as at least a touchdown favorite. Heavier favorites in the Week 4 NFL Vegas lines will come into play later in the day. Eight of those nine NFL games feature NFL spreads of 4.5 points or tighter according to the latest Week 4 NFL odds. It could be a competitive Week 4 NFL schedule, especially during the 1 p.m.
